misfortune

Despite his sudden financial misfortune, he remained optimistic about his future business ventures.

(Chinese) 尽管遭遇了突如其来的财务不幸，他仍对未来的商业投机保持乐观。

The explorer had the misfortune of losing his supplies during a heavy snowstorm in the mountains.

(Chinese) 那位探险家不幸在山里的一场大暴雪中丢失了他的补给品。